Management of type 2 diabetes mellitus.
Dosage & Administration:
The recommended dose of Siglita™ is 100 mg once daily. Siglita™ can be taken with or without food.
For patients with mild renal insufficiency (creatinine clearance [CrCl] 50 mL/min), no dosage adjustment for Siglita™ is required.
For patients with moderate renal insufficiency (CrCl 30 to <50 mL/min), the dose of Siglita™ is 50 mg once daily.
For patients with severe renal insufficiency (CrCl <30 mL/min) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of Siglita™ is 25 mg once daily.
Siglita™ may be administered without regard to the timing of hemodialysis.
Siglita™ Tablet: Box containing 20 tablets in a blister pack.